Sunday, 15 May 2011

Panadol CF

Panadol CF (Cold and Flu) contains the following:

  • An Antipyretic/Analgesic
  • A Decongestant
  • An Antihistamine

Panadol CF contains

Paracetamol, which is an analgesic and antipyretic. The analgesic and antipyretic actions of paracetamol are partly deemed to be due to inhibition of prostaglandin synthesis in the central nervous system. Paracetamol is metabolized in the liver and excreted in the urine mostly as glucuronide and sulphate conjugates - less than 5% is excreted as unmodified paracetamol.

Pseudophedrine is an alpha-adrenergic sympathomimetic nasal decongestant. It acts by stimulating alpha-adrenergic receptors resulting in constriction of the blood vessels of the nasal mucosa. Vasoconstriction of the nasal and sinus mucosal tissue resulting in decreased resistance to airflow through the nasal passages and improved sinus cavity drainage.

Chlorpheniramine Maleate is an antihistamine with a fairly low propensity for sedation that provides temporary relief of runny nose, sneezing, itchy and watery eyes.

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