Metformin Hydrochloride (Metaformin HCL)
Metformin Hydrochloride is an oral antihyperglycemic drug belonging to biguanide class. Metformin aids in the management of type 2 diabetes. Metformin HCL (N,N -dimethylimidodicarbonimidic diamide monohydrochloride) is not chemically or pharmacologically related to sulfonylureas, thiazolidinediones, or (alpha)-glucosidase inhibitors. It is a white to off-white crystalline compound.
Metformin Hydrochloride is an antihyperglycemic agent that improves glucose tolerance in patients, lowering both basal and postprandial plasma glucose.
The absolute bioavailability of a 500mg Metformin HCl tablet under fasting conditions is approximately 50-60%.
Food decreases the entent of and marginally delays the absorption of metformin.